Research Investigates Role of Stress and Parenting on Brain Development

Gary Evans, developmental and environmental psychologist at Cornell University, is PI on a Grand Opportunity award from the National Institutes of Health called "Childhood Poverty and Brain Development: The Role of Chronic Stress and Parenting.". Evans is the Elizabeth Lee Vincent Professor of Human Ecology in the Departments of Design and Environmental Analysis and of Human Development. One fifth of America's children grow up in poverty. While there is good evidence that this is harmful to health, achievement, and socio-emotional adjustment, very little is known about the brain basis that mediates the detrimental effects of poverty.

The two-year research plan will utilize a well-characterized longitudinal sample of low- and middle-income individuals in combination with a comprehensive set of conceptually derived, innovative and validated neuroimaging tests to address two critical questions: How childhood poverty influences adult brain structure and function; and what underlying mechanisms might account for childhood poverty - brain relationships. The invesitgators hypothesize that chronic physiological stress dysregulation as well as harsh, unresponsive parenting during childhood will account for some of the expected linkages between childhood poverty - adult brain structure and function - particularly in the hippocampus, amygdala, and the anterior cingulate/medial prefrontal cortex.

The project will utilize a 14 year, ongoing longitudinal research program of low and middle-income individuals focused on childhood poverty, physiological stress, and socio-emotional development conducted by Evans. Half of this sample (now age 22) grew up below the poverty line and half are middle income. The sample is well characterized over their life course in terms of socioeconomic status and other demographic variables, as well as both physical and psychosocial risk exposures. Primary outcome variables for this longitudinal cohort include multiple methodological indicators of physiological stress (neuroendocrine, cardiovascular, and metabolic) along with parental, self, and teacher ratings of socioemotional development (internalization, externalization, self regulation. In depth data on parenting are also included.

The neuroimaging work will be conducted in the Department of Psychiatry, University of Michigan by Israel Liberzon, with expertise in the neuroimaging of stress in health and mental illness, and by James Swain a child psychiatrist studying the brain basis of parenting.

Read more online at: http://www.human.cornell.edu/che/news_events.cfm?id=180553&rec_date=&pagetype=news-story&related=